Age at menarche, age at natural menopause, and risk of rheumatoid arthritis — a Mendelian randomization study
نویسندگان
چکیده
منابع مشابه
Determinants of Age at Natural Menopause in Shiraz
The mean age at natural menopause and its determinants among Shirazi women (southern Iran) was calculated. The data were obtained from a population- based cross-sectional study carried out in the year 2000. Interviews were carried out and observations made on 948 women who had incurred natural menopause. They were randomly chosen using postal zones housing sample framework of Shiraz.Mean±SD a...
متن کاملAge at Menarche and Time Spent in Education: A Mendelian Randomization Study
Menarche signifies the primary event in female puberty and is associated with changes in self-identity. It is not clear whether earlier puberty causes girls to spend less time in education. Observational studies on this topic are likely to be affected by confounding environmental factors. The Mendelian randomization (MR) approach addresses these issues by using genetic variants (such as single ...
متن کاملRheumatoid arthritis, HLA identity, and age at menarche.
OBJECTIVE To determine whether women with rheumatoid arthritis (RA) had differences in obstetric and gynaecological histories when compared with sisters without RA (controls) METHODS Ninety eight RA discordant sister pairs, 36 of whom were identical for histocompatibility locus antigen (HLA-A, HLA-B, and HLA-Cw) types, were asked to recall their age of menarche, duration of use of contracepti...
متن کاملAge at natural menopause and risk of cardiovascular disease.
BACKGROUND Early natural menopause has been postulated to increase the risk of cardiovascular disease. OBJECTIVE To examine the relation of age at natural menopause with risk of coronary heart disease (CHD) and stroke in the Nurses' Health Study. METHODS Analysis was restricted to 35 616 naturally postmenopausal women who never used estrogen replacement therapy and with no diagnosed cardiov...
متن کاملAge at Natural Menopause and Stroke Mortality
Background and Purpose—Young age at natural menopause has been related to increased cardiovascular mortality, but few studies have examined the relationship with stroke risk specifically. Methods—In a cohort of 19 731 Norwegian women, we analyzed the relationship between age at natural menopause and stroke mortality. A total of 3561 women died of stroke during the 37-year follow-up from 1961 th...
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ژورنال
عنوان ژورنال: Arthritis Research & Therapy
سال: 2021
ISSN: 1478-6362
DOI: 10.1186/s13075-021-02495-x